General Cell Lines and Cell Cultures
Biochain Institute Inc Paraffin Tissue Section Panel - Human Disease Tissue, Alzheimer's Disease, Multi-tissue III, 8 different tissues, 5 slides/PK
BioChain's FFPE Alzheimer's diseased brain tissue panels are designed for rapidly screening Alzheimer's disease-specific genes or proteins in brain tissues. Tissues are arrayed on positively charged glass slides. Alzheimer's diseased brain tissues on T8236444Alz are selected based on functional regions, while those on T8236445Alz are selected based on anatomical regions. T8236564Alz contains both functional and anatomical regions of Alzheimer's diseased brain tissues. Normal brain tissue panels are also available in the identical format as controls. T8236446Alz contains both Alzheimer's diseased brain tissues and normal brain tissues.
Genscript Corporation CHO-K1/GNRHR/G15 Stable Cell
The gonadotropin-releasing hormone receptor (GNRHR) also known as the luteinizing hormone releasing hormone receptor (LHRHR) is a member of the seven-transmembrane G-protein coupled receptor (GPCR) family It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes breast ovary and prostate Upon activation the LHRHr stimulates tyrosine phosphatase and elicits the release of LH from the pituitary Evidence exists showing the presence of LHRH and its receptor in extrapituitary tissues as well as a role in progression of some cancers
ATCC Primary Epidermal Keratinocytes; Normal, Human, Adult
Primary Epidermal Keratinocytes; Normal, Human, Adult (HEKa) are primary cells that provide a complete solution to propagate keratinocytes isolated from human skin. Use these cells in your research in toxicology, wound repair, skin cancer, response to UV radiation, psoriasis, eczema, viral infection, gene delivery systems, cellular differentiation, and cosmetics research/testing.
Promocell GmbH PromoCell Supplement Mix / Preadipocyte Growth Medium
PromoCell Preadipocyte Growth Medium is a low-serum (5% V/V) medium developed for the undifferentiated expansion of human preadipocytes.Although all PromoCell media are optimized for use with primary human cells, we have received feedback from customers that this particular medium can also be used for murine preadipocytes/adipocytes.Components:* Growth Medium (Ready-to-use): Includes Basal Medium and SupplementMix* Growth Medium Kit: Includes Basal Medium and SupplementPack* SupplementMix: Contains all media supplements premixed in one vial* SupplementPack: Contains all media supplements as individual vials| Media supplement | Final supplement concentration|| Fetal Calf Serum | 0.05 ml / ml || Endothelial Cell Growth Supplement | 0.004 ml / ml || Epidermal Growth Factor (recombinant human) | 10 ng / ml || Hydrocortisone | 1 μg / ml || Heparin | 90 μg / ml |
Eurofins Discoverx PathHunter U2OS P2RY1 β-Arrestin Cell Line, 2 vials. (93-0941C3)
The PathHunter P2RY1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY1 and EA-tagged β-Arrestin-2. Activation of P2RY1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS TSHR (Long Isoform) β-Arrestin-1 Cell Line, 2 vials. (93-0912C3)
The PathHunter TSHR(L) (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TSH) based activation of TSHR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TSHR and EA-tagged β-Arrestin-1. Activation of TSHR stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Cell Biologics BALB/C MOUSE PRIMARY,FRZN VIAL
BALB/C Mouse Primary Tracheal and Bronchial Epithelial CellsFrozen vialBALB/c Mouse Primary Tracheal and Bronchial Epithelial Cells from Cell Biologics are isolated from tracheal and bronchial tissues of pathogen-free laboratory mice and then grown in gelatin pre-coated tissue culture flask with Cell Biologics’ Complete Growth Medium. The cells at passage 2-3 are harvested from flasks and cryo-preserved in vials. Each vial contains 0.5x106 cells per ml and is delivered frozen. These primary epithelial cells are isolated using an optimized Cell Biologics methods based on established references. These cells are pre-coated with EpCAM-1 (CD326) antibody, followed by the application of magnetic beads pre-coated with secondary antibody.
Eurofins Discoverx ChemiScreen CXCR3 Chemokine Receptor Membrane Preparation, 1 vial. (HTS003M)
The ChemiScreen CXCR3 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Promocell GmbH PromoCell HFDPC-c 500,000 Human Follicle Dermal Papilla Cells, derived from skin, cryopreserved
Primary Human Follicle Dermal Papilla Cells (HFDPC) are isolated mainly from human dermis of the scalp, originating from the occipital or temple region. Information on donor hair and skin color is available on request. HFDPC stain positive for alkaline phosphatase.Dermal papillae are embedded in a laminin and collagen IV rich extracellular matrix at the base of the hair follicles. They are essential for the induction and maintenance of hair growth. Since they have androgen receptors, they can be used for in vitro screening of androgen blocking reagents.
Eurofins Discoverx PathHunter CHO-K1 rCRTH2 β-Arrestin Cell Line, 2 vials. (93-0580C2)
The PathHunter rCRTH2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin D2) based activation of rCRTH2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rCRTH2 and EA-tagged β-Arrestin-2. Activation of rCRTH2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC HuNS1; Myeloma; Human (Homo sapiens)
HuNS1 is a lymphoblast-like cell from a male with myeloma. This line was derived from the GM4672 cell line (Human Genetic Mutant Cell Repository, Coriell Institute for Medical Research) following ethylmethanesulfonate (EMS) treatment. The cell can be used in immune system disorders and immunology research.
ATCC NCI-H211; Small Cell Lung Cancer; Human (Homo sapiens)
NCI-H211 [H211] is a cell line that was isolated from the lungs of a 50-year-old, White female with carcinoma. This product has applications for cancer research and immunology.
ATCC BT-474 Clone 5; Breast Ductal Carcinoma; Human (Homo sapiens)
BT-474 Clone 5 is an epithelial-like cell line clone that was originally isolated from the mammary gland of a 60-year-old, White female patient with ductal carcinoma. BT-474 (ATCC HTB-20) cells were grown in 10ug/mL Herceptin for several weeks until the resulting cells (clones) were defined as resistant to Herceptin treatment. These resistant cells were grown in standard RPMI with 10% fetal bovine serum for many years under different conditions but the cells enclosed have not been exposed to Herceptin after they were first treated. They were not grown with Herceptin to make sure they stayed resistant. However, these cells have remained resistant for 30+ passages and they still retain the overexpression of HER-2 and are resistant to growth inhibition due to Herceptin.
Abcam LY 303511 dihydrochloride, Negative control for LY 294002, 5MG
MW 379.29 g/mol, Purity >98%. Negative control for LY 294002 (ab120243). PI3K inhibitory activity. Inhibits voltage-gated Kv channel activity (IC₅₀ = 64.6 μM). Various pharmacological effects including inhibition of LPS-stimulated FPR1 expression and induction of H₂O₂ production.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx ChemiScreen CX3CR1 Receptor Stable Cell Line, 2 vials. (HTS015C)
The ChemiScreen CX3CR1 Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. fractalkine) based activation of CX3CR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CX3CR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CX3CR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.